I reckon the two books of the Bible that speak most practically about what we'll face in our daily life are Job & Ecclesiastes:
1. Job - Life's gonna be hard, painful & there are times we'll wish we'd never been born. But God is ultimately watching, and is in control.
2. Ecclesiastes - There's nothing new under the sun and that thing we think will satisfy & make us happy won't. Solomon has been there, tried it & his t-shirt reads 'vanity of vanities...'